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Parkinson’s disease is a rapidly spreading disorder of the nervous system, which affects your activities. It gradually develops. This disease sometimes starts with vibrations that occur in only one hand. But, when vibration becomes the most prominent indication of Parkinson’s disease, it also causes the disorder or the slow activities.
In the early stages of Parkinson’s disease, your face gesture may be reduced or stopped or your arms can stop moving while walking. Your voice may be slow or ambiguous. Over time, symptoms of Parkinson’s disease have become increasingly acute.
Parkinson’s disease is not known due to the disease and it requires a lot of research. Parkinson’s disease can not be cured, but medicines can improve your symptoms. In some cases, therapists may suggest surgery for some areas of your brain and improve symptoms.
The symptoms and signs of this disease can vary in every person. Early signs can be low and do not easily attract anyone’s attention towards yourself. Its symptoms often begin to appear on one side of your body and the condition worsens. After this the whole body seems to be affected by the symptoms.
Indications and symptoms of Parkinson’s disease may include the following –
Vibration: Shaking or moving usually starts with your hands or fingers. Due to this, your thumb and index finger may begin to rub each other, called “Pill-Rolling Tremor”. One of the symptoms of Parkinson’s disease is the restlessness in your hands in a relaxed state.
Slow activity (bradychinasia): Over time, this disease can reduce your ability to move and work, due to which there is difficulty in doing an easy task and time is high. Your walking speed may be slow or you may have difficulty standing. Apart from this, you try to drag the feet down, which makes it difficult to walk.
Hard muscles: Muscle stiffness may occur in any part of your body. Strict muscles can limit your speed and cause pain.
Deteriorating currency and imbalance: As a result of Parkinson’s disease, your body may bend or the problem of imbalance can be.
Loss of automated activities: In Parkinson’s disease, the ability to do unconscious acts may decrease, including blinking of the eyelids, smiling or moving the hands. While talking, you can not have greed for a long time on your face.
Change in voice: As a result of Parkinson’s disease, accentual problems can occur. Your vocabulary can be slow, intense and unclear or you may feel hesitant before talking. Your sound becomes much worse than normal infection. Vocals and language practitioners can help in troubleshooting your pronunciation problems.
Change in handwriting: The handwriting may be small and may be difficult to write.
Medicines can reduce many of these symptoms. See the section “Treatment” below for more information.
If you see any symptoms related to Parkinson’s disease, contact your doctor. Consult the physician also to test your condition and to address other causes of symptoms.
Due to Parkinson’s disease:
In Parkinson’s disease, some nerve cells (neurons) present in the brain gradually get spoiled or destroyed. Neurons produce chemicals called dopamine in our brain.
Due to the destruction of these neurons many symptoms arise. The decrease in dopamine levels causes abnormal brain activity, which results in signs of Parkinson’s disease.
Genes: Researchers have identified specific genetic mutations, which can cause Parkinson’s disease. However, these are unusual except for rare cases of Parkinson’s disease-related family members.
Environmental reasons: The effect of some toxic substances or environmental factors can increase the risk of Parkinson’s disease of the last stage, but overall they have less risk of Parkinson’s disease.
In essence, more research is needed to identify responsible factors for Parkinson’s disease.
Risk factors of Parkinson’s disease include:
Increasing age: Parkinson’s disease is rarely found in young people. It usually starts in the middle or the last stages of life and the risk increases with age. This disease usually develops in people 60 years of age or older.
Heredity: Due to the Parkinson’s disease being related to one of your close relatives, you are more likely to get this disease. However, as long as many members of your family do not get this disease, then your risk is low.
Men more risk: Men are more likely to develop Parkinson’s disease than women.
Exposure to toxic substances: In the constant contact of herbicides and insecticides, your risk of Parkinson’s disease can be slightly increased.
How can preventing Parkinson’s disease?
Since the cause of this disease is unknown, therefore its methods of prevention are also a mystery. However, some research has shown that caffeine found in coffee, tea and coca cola can reduce the risk of developing Parkinson’s disease. Green tea may also be helpful in reducing its risk.
Some research has shown that regular aerobic exercise can reduce the risk of this disease.
How to diagnose / diagnose Parkinson’s disease?
There is currently no special investigation to test Parkinson’s disease. In the conditions of nervous system, the trained neurologist will diagnose your medical history, your signs and symptoms, and on the basis of a neurological and physical examination. At the same time, your physician may recommend testing to overcome other conditions, which may be the cause of your symptoms.
In addition to the test, doctors can give you Parkinson’s drug ‘carbidopa-levodopa’. If taking this medicine significantly improves it, it is often considered a confirmation of Parkinson’s disease. Sufficient doses should be given to see the effect of the drug, because lower dosage is not beneficial for one or two days. For the best response the drug should take empty stomach at least one hour before eating it. Sometimes it takes a long time to diagnose the disease. In order to evaluate your condition and symptoms from time to time, and to diagnose the disease, you may suggest regular examination of a trained neurologist.
What is the treatment of Parkinson’s disease?
Parkinson’s disease can not be cured, but medicines can help to control your symptoms. In some serious cases, surgery can be advised.
Your doctor may also recommend changes in lifestyle, especially aerobic exercise. In some cases, physical therapy is also very important. It is emphasized on balance and stretching.
Medicines can help in relieving problems related to your movements, activity and tremor by increasing the supply of dopamine in your brain. However, dopamine can not be given directly because it can not enter your brain.
After the treatment of Parkinson’s disease begins, there may be significant improvement in your symptoms. Over time, the effects of medicines are often reduced, though the symptoms can usually be controlled very well.
Your doctor may prescribe the following medicines –
Levodopa is the most effective drug in Parkinson’s disease. It is a natural chemical that goes into your brain and gets converted into dopamine. Nausea or dizziness (orthostatic hypotension) can have side effects.
After several years, when your disease increases, the effect of levodopa medication can not be stable and may be more or less. Apart from this, you may experience involuntary activities (Dyskensia) after having a higher dose of levodopa. Your doctor may reduce your dose of medication or regulate the time taken for medication to control these effects.
Agonists produce dopamine-like effects in the brain. These Parkinson’s are not as effective as Levodopa in treating the symptoms of the disease. However, their effects last longer and they can be used with levodopa in order to reduce the greater effect of levodopa. Some side effects of dopamine agonists are similar to levodopa, but they include hallucinations, swelling, sleepiness, and repeated behaviors – such as playing gambling –
These help prevent brain damage of dopamine by blocking the brain enzyme called monoaman oxidase B (MAO-B). This enzyme divides the brain into dopamine into smaller sections. Side effects may include nausea or headache. Taking these drugs with levodopa increases the risk of hallucinations. Due to the serious but rare effects, these drugs are often not used in combination with antidepressants or certain types of nerotics. Contact your doctor before taking any additional medication with Mao-B Inhibitors.
Catechol o-methyltransferase (COT) inhibitor
This drug enhances the effect of levodopa therapy by blocking the enzyme that breaks the dopamine. Side effects include the risk of involuntary activity (dyskinesia), which increases mainly due to the effects of levodopa’s dietary dosage. Other side effects include side effects caused by high amounts of diarrhea or levodopa.
These medicines have been used for many years to control vibrations associated with Parkinson’s disease. However, the slight advantages of these drugs often do not affect the side effects, such as weakness in memory, delusions, hallucinations, constipation, dryness in the mouth and problems in urine.
With the initial stage of Parkinson’s disease symptoms, you can suggest doctor amantadine for some time. It can also be given with Levodopa therapy at the later stages of Parkinson’s disease to control the involuntary activities (dyskennesia) induced by Carbidopa Levodopa. The side effects may include a purple spot on the skin, ankle swelling or hallucinations.
Deep brain stimulation (DBS) – In the surgeon implants the electrode in a specific part of your brain. The electrodes are attached to the implanted generator in your chest near your collarbone. They send electrons in your brain and can reduce the symptoms of Parkinson’s disease.
The risks associated with surgery include infection, stroke or brain hemorrhage. Some people have to face problems related to the DBS system or experience complications due to stimulation. Your doctor may need to adjust or change some parts of the related system.
Deep DBS is used mostly for people suffering from high-stage Parkinson’s disease, who respond to unstable responses to the Levodopa drug.
DBS can continue to improve the symptoms of Parkinson’s disease, and these remain after several years of improvement. However, DBS Parkinson can not completely stop the disease from growing.
What other problems can be caused by Parkinson’s disease?
Parkinson’s disease often occurs with the following additional problems that can be cured –
Hard to think: You may experience cognitive problems (dementia / dementia) and difficulty in thinking. This usually happens in the later stages of Parkinson’s disease. Such cognitive problems (Cognitive Problems) do not show a more positive response to medicines.
Depression and emotional changes: A person with Parkinson’s disease may have a depression. You can also experience other emotional changes, such as fear of fear, anxiety or motivation. Doctors can give you medicines to treat these symptoms.
Swallowing Problems: If there is progress in your situation, you may have problems related to swallowing. This is not a serious problem in specific Parkinson’s disease. Due to gradual swallowing, saliva may accumulate in your mouth and drip out of the mouth due to swallowing.
Sleep problems: People with Parkinson’s disease often have sleeping problems, such as sleeping in the night, getting up early or sleeping in the daytime.
Bladder related problems: Bladder problems can arise in this disease, including inability to control urine or pain or trouble in urinating. (Read more – UTI treatment)
Constipation: Many people with Parkinson’s disease get constipation, mainly due to the slow functioning of the digestive system.
You can also experience the following –
Changes in blood pressure: When you are standing due to a sudden reduction in blood pressure (orthostatic hypotension), you may feel dizziness or weakness.
Sniffing trouble: You may experience hormonal problems. You may have difficulty finding an odor or finding the difference between one or more odor.
Fatigue: Difficulty finding the difference between or more than one smell can be difficult.
Fatigue – Many people with this disease lack energy and they feel tired
Pain: Many people in this illness either have pain in specific parts of the body or in the whole body.
Sexual dysfunction: Some people suffering from this disease often lose libido.
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